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Saturday 26 November 2011

Study suggests link between early Alzheimer's disease and low body mass index (BMI)


Published 22 November 2011
People in the earliest stages of Alzheimer's disease may be more likely to have a lower body mass index according to a study published in Neurology (Monday 21 November 2011).
Scientists at the Department of Neurology and School of Medicine, University of Kansas Medical Centre, used advanced brain imaging techniques and analyses of cerebrospinal fluid to look for biomarkers for Alzheimer's disease in 506 people.
The study found that people with a low BMI were more likely to have biomarkers forAlzheimer's disease, whether they had mild cognitive impairment or not.
Alzheimer's Society comment:
'As yet it is unclear whether a low BMI is actually part of Alzheimer's, or a side effect caused by the disease. Although this study shows a link between it and changes in the brain common to Alzheimer's, there was no association between BMI and symptoms of the disease such as memory loss. More work is needed before we can say if these findings could be used to develop better ways ofdiagnosing the early stages of the condition.
What we do know is that living well will reduce your risk of developing Alzheimer's disease. Alzheimer's Society recommends people eat healthily and exercise regularly.'

Dr Anne Corbett
Research Manager
Alzheimer's Society
Research Reference:
Alzheimer disease biomarkers are associated with body mass index by J.M Burns et al in NEUROLOGY® the medical journal of the American Academy of Neurology.

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